Archive for ◊ December, 2010

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Autoimmune Disorders
Aseptic meningitis has also been associated with autoimmune diseases. In particular, approximately 2% to 4% percent of patients with systemic lupus erythematosus may develop aseptic meningitis. In addition to malaise, fever, and headache, aseptic meningitis due to systemic lupus erythematosus may be accompanied by myelopathy, stroke, and decreased serum complement levels. The CSF typically has a neutrophilic pleocytosis.

Malignancy
Central nervous system tumors may manifest as acute or recurrent aseptic meningitis. This may result from direct invasion of the meninges with the tumor, and there may be involvement from leukemia, lymphoma, or metastatic tumors. A chemical meningitis, caused by lipid spillage from tumors such as craniopharyngiomas or pituitary adenomas, may also occur. Aseptic meningitis due to a malignancy may cause a very low glucose level. In addition, patients may present with focal neurologic findings. Neuroimaging is warranted. The prognosis is usually poor.

Mollaret’s Meningitis
Mollaret’s meningitis is a rare syndrome of recurrent acute meningitis. The symptoms of an individual episode will resolve spontaneously in 2 to 6 days but then recur in weeks to months. The disease is most common in young adults. The CSF demonstrates a mixed lymphocytic and neutrophilic pleocytosis. Early in an attack, large fragile mononuclear cells are seen, which have been demonstrated to be monocytes. Studies have shown links with HSV 1 and 2 as well as Epstein-Barr virus.
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Author: admin

Skin picking has been described in the professional literature, particularly the dermatology literature, for many years, but it’s been little researched. Traditionally, this behavior has been considered a type of “neurotic excoriation,” a broad and antiquated term used for more than 100 years that doesn’t specify the cause of the picking or indicate treatment approaches. Not all people who pick their skin have BDD. Skin picking can occur as a symptom of other psychiatric disorders. In some cases, it’s simply a habit rather than a symptom of a disorder.
To determine whether picking is a symptom of BDD, ask the person why they pick. Do they pick to remove or minimize supposed defects or imperfections in their appearance, such as pimples, bumps, acne, or scars? If so, and if the other criteria for BDD are met, the picking behavior is a symptom of BDD. It’s often a clue to the diagnosis.
But often the picking is kept secret. Many people are very ashamed of this behavior and reluctant to reveal it to others. One adolescent who was referred to me because of his picking talked at length about other, more minor problems and didn’t mention his picking at all. When I finally asked him about it, he acknowledged that it was his major problem but that he’d been too embarrassed to bring it up.
But some people talk about it quite openly. One young woman I saw not only talked about it with others—she even picked her friends’ skin. “I can’t stand to see anyone with things on their face,” she explained. “I have to make their face smooth! When I see them, I pick off the little imperfections. They’re my friends, so they let me do it.” Another woman told me, “I look for anything to pick. I want to pick my friends’ skin because I pick my own and there’s nothing left. I especially like to peel other peoples’ backs when they’re sunburned.” She also liked to peel paint off walls, paper off jars, and dried glue off her hands.
People with BDD who pick are similar in many ways to those with BDD who don’t pick. But there are some interesting differences. Although skin concerns are common in both groups, those who pick are more likely than those who don’t to be concerned with their skin (close to 100% versus about 50%).
They’re also more likely to excessively groom and camouflage, perhaps because they sometimes do create actual skin defects that they feel they need to cover. People with BDD who pick their skin are also more likely than those who don’t pick to have actual skin defects, as opposed to none. Sometimes the minimal defects lead to the picking, and often they result from the picking. A vicious cycle can occur in which a minimal defect leads to picking behavior, which then creates more defects and more picking. Sometimes, skin defects caused by the picking are clearly present and noticeable.
People who pick their skin are also more likely to be treated by a dermatologist: approximately two-thirds versus fewer than one-third. Although dermatologic treatment is sometimes needed to treat the skin damage or infections that the picking can cause, it usually doesn’t decrease BDD symptoms (the skin-related preoccupations and associated picking).
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Author: admin

Язвенная болезнь — это  хроническое рециди­вирующее заболевание, характеризующееся формировани­ем язвы в желудке или в двенадцатиперстной кишке вследствие расстройства общих и местных механизмов нервной и гормональной регуляции основных функций гастродуоденальной системы, нарушения трофики и протеолиза слизистой оболочки.
Язвенная болезнь широко распространена во всех странах мира и встречается у 2—3% взрослого населения, причем в 2 раза чаще у жителей города.
Мужчины, особенно молодого возраста, болеют язвенной болезнью в 4 раза чаще, чем женщины. Почти у каждой третьей женщины она возникает после наступле­ния менопаузы. Локализация язвы в двенадцатиперст­ной кишке характерна для подростков и мужчин молодого возраста, а в желудке — для женщин и мужчин среднего, пожилого и старческого возраста.
Основной причиной возникновения язвен­ной болезни является длительное или часто повторяю­щееся психоэмоциональное перенапряжение, преимущест­венно негативного характера (отрицательные эмоции, конфликтные ситуации, чувство постоянной тревоги, пере­утомление и т. д.). Психоэмоциональное перенапряже­ние наиболее характерно для людей молодого возраста, которые в этот период жизни завершают учебу в школе, поступают в высшие учебные заведения,  трудоустраиваются и т. д. Пред­располагающими факторами служат наследственная отягощенность, нарушения в питании (еда всухомятку, нерегулярный прием пищи, употребление грубой, острой пищи, плохое пережевывание ее при быстрой еде и болез­нях зубов, а также недостаточное содержание в пищевых
продуктах белков и витаминов, избыточное потребление углеводов), курение, употребление алкоголя.
Особенности клинического проявле­ния язвенной болезни в зависимости от локализации объясняются выраженностью секреторных и двигательных расстройств как в процессе пищеварения, так и в меж пищеварительном периоде, а также напряженностью и функциональной активностью того или иного отдела желудка и двенадцатиперстной кишки по обеспечению переваривания пищи и эвакуации ее в дистальные отделы желудочно-кишечного тракта.
Язвенная болезнь отличается часто возникающей изжогой и приступообраз­ной болью натощак, ночью, спустя 1,5—2 ч после еды. Стойко повышены кислотность и протеолитическая актив­ность желудочного сока, характерны рас­стройства желудка и двенадцатиперстной кишки. Неред­ко первым проявлением болезни бывает желудочно-кишечное кровотечение.

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Category: Gastrointestinal  | Comments off
Author: admin

Tree pollens, grass pollens, and weed pollens cause allergic nasal symptoms in millions of people. Pollen is that part of plants that contains the male genetic material. The units in which this material is held are called pollen grains. Two walls surround the genetic material in each grain. The innermost wall, the intine, is very thin and fragile. The outer protective wall, the exine, is relatively thick and highly resistant to destruction. Pollen grains from different plants look as different from one another as do the plants from which they come, a fact which is best appreciated when the grains are stained with special chemicals and viewed under a microscope. This is, in fact, what is done when a pollen count is made. Stained pollen grains are beautiful, intricate structures. For example, ragweed pollen resembles a golf ball, oak pollen an intergalactic star-fighter, and cypress pollen, Рас Man.
Pollination is the term used to describe the transfer of pollen grains from the anther, the male organ of plants, to the stigma, the female organ of plants. Once transfer is completed, fertilization can take place. Surprisingly, only a small percentage of the thousands of plant pollens that exist are released into the air under circumstances sufficient to allow them to cause nasal allergy symptoms.
For a pollen to cause nasal allergies, it must meet four requirements:
- It must be produced in massive quantities.
- Its primary process of pollination must be via wind, not insects.
- It must be able to stimulate our immune system to produce an allergic response.
- We humans must be sufficiently exposed to the pollen to develop an allergy.

In order to be successfully wind pollinated, a plant and its pollen must have the following characteristics:
- A large number of pollen grains must be produced.
- The pollen must be aerodynamically sound, i.e., it must be of the right size, structure, and weight to be carried by the wind.
- The structure of the plant and its geographic location must favor the release of pollen into the wind.
- Pollen release during the season and during the day must be timed to optimize capture by the female organ.
- Like plants should be closely spaced to one another.
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